Darlene Gandolfi

Darlene Gandolfi

Professor, Chemistry

Brownson Hall, Room 3B
In-person office hours are suspended. Please call or email for a virtual appointment.
1 (914) 323-5475

About Me

Dr. Darlene D'Alliessi Gandolfi is a Professor of Chemistry at Manhattanville College.  After receiving her B.A., summa cum laude, from Manhattanville, Dr. Gandolfi went on to earn an M.S. and Ph.D. in chemistry from Yale University. Before returning to Manhattanville as a full-time faculty member, she worked as a postdoctoral research associate at Princeton University. Dr. Gandolfi's research interests include chirality in organometallic complexes, asymmetric catalysis, and synthesis of chemotherapeutic drugs. She has also collaborated with her students on research projects in food chemistry, environmental chemistry, and the chemistry of herbal remedies. Her research has been published in the Journal of the American Chemical Society, Organometallics, Retrovirology, and PLoS ONE. Research on which she has collaborated has been presented at professional conferences in Turkey, Australia, South Africa, Canada, and within the USA.

Current Courses
Principles of Chemistry I (Fall)
Principles of Chemistry I Lab (Fall)
Introduction to Chemistry (Spring)
Principles of Chemistry II (Spring)
Principles of Chemistry II Lab (Spring)
Intermediate Inorganic Chemistry (Spring)
Professional History
Professor of Chemistry
Manhattanville College
Associate Professor of Chemistry
Manhattanville College
Assistant Professor of Chemistry
Manhattanville College
Research Associate, Chemistry Department
Princeton University
Chemistry, Ph.D., Yale University
Chemistry, M.S., Yale University
Chemistry, B.A., Manhattanville College
Feature Publications

Article May 18, 2016

"Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial"

PLoS ONE 2016, 11(5): e0154842. doi:10.1371/journal.pone.0154842


Research Paper

“Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection”

PLoS ONE 2013, 8(9): e74414. doi:10.1371/journal.pone.0074414

Research Paper September 06, 2012

"Abrogating HIV-1 Infection via Drug-Induced Reactivation of Apoptosis"

US Patent Application 20120225093

Research Paper

“Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A”

Retrovirology 2009, 6, 90

Research Paper April 13, 2006

“Method of Improving Drugs with Anti-Retroviral and Anti-Cancer Activity”

World Intellectual Property Organization Patent #WO/2006/039697

Research Paper

“Planar Chirality in Tethered η6: η 1-(Phosphinophenylenearene) Ruthenium(II) Complexes and Their Potential Use as Asymmetric Catalysts”

Organometallics 2003, 22, 2749-2757

Research Paper

“Tunable Stereoselective Hydrosilylation of PhC≡CH Catalyzed by Cp*Rh Complexes”

Organometallics 2002, 21, 1743-1746

Research Paper December 11, 2014

“An Application of Electronic Asymmetry to Highly Enantioselective Catalytic Diels-Alder Reactions”

Journal of the American Chemical Society 2001, 123, 2525-2529