Darlene Gandolfi

Darlene Gandolfi

Professor, Chemistry

Brownson Hall, Room 117/3B
Spring 2018 (1/23/18-5/4/18): Tuesdays 1:45 - 3:45 PM; Fridays 1:45 - 2:45 PM; Other times by appointment
darlene.gandolfi@mville.edu
1 (914) 323-5475

About Me

Dr. Darlene D'Alliessi Gandolfi is a Professor and Chairwoman of the Chemistry Department at Manhattanville College. She also serves as the campus pre-health professions advisor. After receiving her B.A., summa cum laude, from Manhattanville, Dr. Gandolfi went on to earn an M.S. and Ph.D. in chemistry from Yale University. Before returning to Manhattanville as a full-time faculty member, she worked as a postdoctoral research associate at Princeton University. Dr. Gandolfi's research interests include chirality in organometallic complexes, asymmetric catalysis, and synthesis of chemotherapeutic drugs. She has also collaborated with her students on research projects in food chemistry, environmental chemistry, and the chemistry of herbal remedies. Her research has been published in the Journal of the American Chemical Society, Organometallics, Retrovirology, and PLoS ONE. Research on which she has collaborated has been presented at professional conferences in Turkey, Australia, South Africa, Canada, and within the USA.

Current Courses
Principles of Chemistry II
Intermediate Inorganic Chemistry
Professional History
Professor of Chemistry
Manhattanville College
Associate Professor of Chemistry
2010-2017
Manhattanville College
Assistant Professor of Chemistry
2004-2010
Manhattanville College
Research Associate, Chemistry Department
2003-2004
Princeton University
Education
Chemistry, Ph.D., Yale University
Chemistry, M.S., Yale University
Chemistry, B.A., Manhattanville College
Feature Publications

Article May 18, 2016

Co-author
"Drug-Based Lead Discovery: The Novel Ablative Antiretroviral Profile of Deferiprone in HIV-1-Infected Cells and in HIV-Infected Treatment-Naive Subjects of a Double-Blind, Placebo-Controlled, Randomized Exploratory Trial"

PLoS ONE 2016, 11(5): e0154842. doi:10.1371/journal.pone.0154842

Research Paper

Co-author
“Drug-Induced Reactivation of Apoptosis Abrogates HIV-1 Infection”

PLoS ONE 2013, 8(9): e74414. doi:10.1371/journal.pone.0074414

Research Paper September 06, 2012

Co-author
"Abrogating HIV-1 Infection via Drug-Induced Reactivation of Apoptosis"

US Patent Application 20120225093

Research Paper

Co-author
“Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A”

Retrovirology 2009, 6, 90

Research Paper April 13, 2006

Co-author
“Method of Improving Drugs with Anti-Retroviral and Anti-Cancer Activity”

World Intellectual Property Organization Patent #WO/2006/039697

Research Paper

Co-author
“Planar Chirality in Tethered η6: η 1-(Phosphinophenylenearene) Ruthenium(II) Complexes and Their Potential Use as Asymmetric Catalysts”

Organometallics 2003, 22, 2749-2757

Research Paper

Co-author
“Tunable Stereoselective Hydrosilylation of PhC≡CH Catalyzed by Cp*Rh Complexes”

Organometallics 2002, 21, 1743-1746

Research Paper December 11, 2014

Co-author
“An Application of Electronic Asymmetry to Highly Enantioselective Catalytic Diels-Alder Reactions”

J. Am. Chem. Soc. 2001, 123, 2525-2529