Christopher J. Pappas

Christopher J. Pappas, Ph.D.

Associate Professor, Chair, Biology

Brownson Hall, Room 225
Tuesday & Friday 10:35AM-12:05PM
1 (914) 323-1276

About Me

Classically trained as a molecular microbiologist, Dr. Pappas teaches students in lectures and laboratories within the disciplines of general biology, parasitology, genetics, molecular biology, biochemistry, and nutrition. His research has included studies involving Borrelia burgdorferi, the etiologic agent of Lyme disease, in which he focused specifically on the the survival of the bacteria when inside the tick. His current research interests include genetic mechanisms of survival within saprophytic Leptospira, as well as other vector-borne and enzootic diseases. Outside of the laboratory and classroom, Dr. Pappas is involved in community activities such as judging at annual science fairs and working within Manhattanville College’s Organic Community Garden.

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Current Courses
Principles of Biology I
Contemporary Nutrition
Principles of Genetics
Molecular Biology Techniques
Senior Research
Senior Evaluation
Professional History
Associate Professor
Manhattanville College
Visiting Researcher
Institut Pasteur, Paris, France
Microbiology and Immunology, Ph.D., New York Medical College
Microbiology and Immunology, M.S., New York Medical College
Psychology, B.S., Syracuse University
Feature Publications

Research Paper

“Control of gene expression in Leptospira spp. by Transcription Activator-Like Effectors (TALEs) demonstrates a potential role for LigA and LigB in virulence in L. interrogans.”

Applied and Environmental Microbiology 2015 Nov; Vol. 81, no. 22

Research Paper

“A replicative plasmid vector Allows efficient complementation of pathogenic Leptospira strains”

Applied and Environmental Microbiology. 2015 May; Vol 81 (9).

Research Paper

“Characterization of the RelBbuRegulaon in Borrelia burgdorferi Reveals Modulation of Glycerol Metabolism by (p)ppGpp..”

PLoS One, Feb 2015 Vol.

Research Paper

"Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle"

PLoS Pathogens 2011 Jul;7(7):e1002102. Epub 2011 Jul 7

Research Paper

"BB0844, an RpoS-regulated protein, is dispensable for Borrelia burgdorferi infectivity and maintenance in the mouse-tick infectious cycle."

Infection and Immunity. 2011 Mar;79(3):1208-17

Research Paper

"Fitness variation of Borrelia burgdorferi sensu stricto strains in mice"

Applied Environmental Microbiology. 2008 Jan, 74 (1): 153-7

Awards & Grants

Federal Award ID IIA-1159099: “Characterizing the Function of Leptospiral Proteins in the Biology of Genus Leptospira.” Office of International Science and Engineering, National Science Foundation. Award total: $159,222. June 2013-May 2015.
Faculty Member of the Year Award.  Awarded by the Student Government Association, Manhattanville College. April 2013.