Christopher J. Pappas, PhD
Professor, Biology
Brownson Hall, Room 225
christopher.pappas@mville.edu
(914) 323-1276
Classically trained as a molecular microbiologist, Dr. Pappas teaches students in lectures and laboratories within the disciplines of general biology, parasitology, genetics, molecular biology, biochemistry, nutrition, and related nursing courses. His research has included studies involving Borrelia burgdorferi, the etiologic agent of Lyme disease, in which he focused specifically on the the survival of the bacteria when inside the tick. His current research interests include genetic mechanisms of survival within saprophytic Leptospira, as well as other vector-borne and enzootic diseases. Outside of the laboratory and classroom, Dr. Pappas is involved in community activities, such as judging at annual science fairs and working within Manhattanville College’s organic community garden.
Psychology, BS, Syracuse University
Microbiology and Immunology, MS, New York Medical College
Microbiology and Immunology, PhD, New York Medical College
Chapter
Co-Author“Creating a Library of Random Transposon Mutants in Leptospira”
Research Paper
Co-AuthorA Novel Ex Vivo Biosassay Suggests DEET is an Effective Repellent of Rhipicephalus Sanguineus
Genome-Wide Transcriptional Start Site Mapping and sRNA Identification in the Pathogen Leptospira Interrogans
The EbpA-RpoN regulatory pathway of the pathogen Leptospira interrogans is essential for the survival in the environment
Research Paper
Co-author“A replicative plasmid vector Allows efficient complementation of pathogenic Leptospira strains”
Research Paper
Co-author“Control of gene expression in Leptospira spp. by Transcription Activator-Like Effectors (TALEs) demonstrates a potential role for LigA and LigB in virulence in L. interrogans.”
Research Paper
Co-author“Characterization of the RelBbu Regulon in Borrelia burgdorferi Reveals Modulation of Glycerol Metabolism by (p)ppGpp..”
Research Paper
Co-author“Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle”
Research Paper
Co-author“BB0844, an RpoS-Regulated Protein, Is Dispensable for Borrelia burgdorferi Infectivity and Maintenance in the Mouse-Tick infectious Cycle.”
Research Paper
Co-author“Fitness variation of Borrelia burgdorferi sensu stricto strains in mice”
Federal Award ID IIA-1159099: “Characterizing the Function of Leptospiral Proteins in the Biology of Genus Leptospira.” Office of International Science and Engineering, National Science Foundation. Award total: $159,222, June 2013-May 2015
Faculty Member of the Year Award. Awarded by the Student Government Association, Manhattanville College, April 2013
Faculty Advisor of the Year Award. Awarded by the Student Government Association, Manhattanville College, May 2020