Christopher J. Pappas

Christopher J. Pappas, Ph.D.

Professor, Biology

Brownson Hall, Room 225
Tuesday & Friday 10:35AM-12:05PM
christopher.pappas@mville.edu
1 (914) 323-1276

About Me

Classically trained as a molecular microbiologist, Dr. Pappas teaches students in lectures and laboratories within the disciplines of general biology, parasitology, genetics, molecular biology, biochemistry, nutrition, and related nursing courses. His research has included studies involving Borrelia burgdorferi, the etiologic agent of Lyme disease, in which he focused specifically on the the survival of the bacteria when inside the tick. His current research interests include genetic mechanisms of survival within saprophytic Leptospira, as well as other vector-borne and enzootic diseases. Outside of the laboratory and classroom, Dr. Pappas is involved in community activities such as judging at annual science fairs and working within Manhattanville College’s Organic Community Garden.

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Current Courses
Principles of Biology I
Contemporary Nutrition
Principles of Genetics
Parasitology
Molecular Biology Techniques
Research Methods in the Life Sciences
Professional History
Professor
Manhattanville College
Visiting Researcher
Institut Pasteur, Paris, France
Education
Microbiology and Immunology, Ph.D., New York Medical College
Microbiology and Immunology, M.S., New York Medical College
Psychology, B.S., Syracuse University
Feature Publications

Chapter

Co-Author
"Creating a Library of Random Transposon Mutants in Leptospira"

Methods in Molecular Biology vol 2134 2020

Link to article

Research Paper

Co-Author
A novel ex vivo biosassay suggests DEET is an effective repellent of Rhipicephalus sanguineus

Journal of Agricultural and Urban Entomology. 2017. Vol 33 (1):19-31

Link to article

Co-Author
Genome-Wide Transcriptional Start Site Mapping and sRNA Identification in the Pathogen Leptospira Interrogans

Frontiers in Cellular and Infection Microbiology. 2017 Jan:7:10.

Link to article

Co-Author
The EbpA-RpoN regulatory pathway of the pathogen Leptospira interrogans is essential for the survival in the environment

Applied and Environmental Microbiology. 2017 Jan; Vol 83 (3).

Link to article

Research Paper

Co-author
“A replicative plasmid vector Allows efficient complementation of pathogenic Leptospira strains”

Applied and Environmental Microbiology. 2015 May; Vol 81 (9).

Link to article

Research Paper

Co-author
“Control of gene expression in Leptospira spp. by Transcription Activator-Like Effectors (TALEs) demonstrates a potential role for LigA and LigB in virulence in L. interrogans.”

Applied and Environmental Microbiology 2015 Nov; Vol. 81, no. 22

Link to article

Research Paper

Co-author
“Characterization of the RelBbu Regulon in Borrelia burgdorferi Reveals Modulation of Glycerol Metabolism by (p)ppGpp..”

PLoS One, Feb 2015 Vol.

Link to article

Research Paper

Co-author
"Borrelia burgdorferi requires glycerol for maximum fitness during the tick phase of the enzootic cycle"

PLoS Pathogens 2011 Jul;7(7):e1002102. Epub 2011 Jul 7

Link to article

Research Paper

Co-author
"BB0844, an RpoS-regulated protein, is dispensable for Borrelia burgdorferi infectivity and maintenance in the mouse-tick infectious cycle."

Infection and Immunity. 2011 Mar;79(3):1208-17

Link to article

Research Paper

Co-author
"Fitness variation of Borrelia burgdorferi sensu stricto strains in mice"

Applied Environmental Microbiology. 2008 Jan, 74 (1): 153-7

Link to article

Awards & Grants

Federal Award ID IIA-1159099: “Characterizing the Function of Leptospiral Proteins in the Biology of Genus Leptospira.” Office of International Science and Engineering, National Science Foundation. Award total: $159,222. June 2013-May 2015.
 
Faculty Member of the Year Award.  Awarded by the Student Government Association, Manhattanville College. April 2013.

Faculty Advisor of the Year Award.  Awarded by the Student Government Association, Manhattanville College. May 2020.